PT-141

Description

Product Overview
Featuring PT-141 (Bremelanotide), a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). PT-141 demonstrates selective agonist activity at melanocortin receptors, particularly MC3R and MC4R pathways, making it valuable for neurological signaling research. Laboratory studies suggest this peptide may potentially influence central nervous system-mediated responses and melanocortin pathway activation in controlled research models. Research indicates PT-141 could possibly affect neurotransmitter signaling, receptor binding dynamics, and CNS-mediated physiological responses in tissue samples.
This research-grade product contains PT-141 (10mg) in a single sterile vial.

Quality Standards

Greater than 98% pure
Endotoxin-free
Sterility guaranteed

Structure & Specification
PT-141 Peptide Summary
Product Specifications: Lyophilized Powder (>98% purity) in 3ml vial.
*Requires Reconstitution with solvent such as BAC Water
Application: Research peptide with potential in neurological and melanocortin pathway studies
Appearance: Solid, white to off-white powder in 3mL glass ampule
Chemical Formula: C50H68N14O10
PubChem CID: 9941945
CAS Number: 189691-06-3
Molecular Weight: 1025.2 g/mol
Synonyms: PT-141, PT141, Bremelanotide, BMT
Storage: Store at ≤-20°C, sealed, away from heat, light, and moisture.
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Half-Life: Approximately 2-3 hours in research models
Sourcing Standards

Raw ingredients manufactured by an FDA registered & audited supplier following cGMP standards
Finished peptides 0.22 µm sterile-filtered (aseptically processed) and produced in a GMP facility
Tested by a US FDA registered & audited third-party analytical lab accredited by ISO/IEC and U.S. Department of Ecology

Always Quality-Tested, Verified With Third Party COA’s

At every step, we prioritize quality by conducting rigorous third-party testing on all our products. These tests focus on four key characteristics: identity, purity, sterility, and endotoxicity, ensuring that each batch meets the highest standards for safety and performance, with independent third party Certificates of Analysis (COAs) to verify our commitment to excellence.
Identity Test
Identity testing ensures that the product contains the correct ingredient as labeled, verifying its authenticity and matching it to established reference standards through advanced analytical methods including HPLC and mass spectrometry.
Purity Test
Purity and concentration testing verifies that PT-141 is present in the correct amount, with a purity of 98% or higher to meet stringent quality standards. Our analytical testing includes amino acid analysis and peptide sequencing verification.
Sterility Test
Sterility testing ensures that the product is completely free from bacteria, fungi, and other microorganisms, meeting USP <71> sterility requirements for research-grade peptides.
Endotoxin Test
Endotoxin testing confirms bacterial endotoxin levels are below detectable limits (<1.0 EU/mg), ensuring product safety and research integrity through LAL (Limulus Amebocyte Lysate) testing methods.

Research Applications

Melanocortin receptor pathway studies
Central nervous system signaling research
Neuropharmacology investigations
Receptor binding and activation studies
Behavioral pharmacology research
CNS-mediated response mechanism studies

Handling & Storage Guidelines

Store lyophilized powder at -20°C or below
Protect from light and moisture
Once reconstituted, store at 2-8°C for short-term use
For long-term storage of reconstituted solution, store at -20°C
Avoid repeated freeze-thaw cycles
Use appropriate sterile technique during reconstitution

Research Notes

PT-141 has been extensively studied in laboratory settings for its melanocortin receptor activity. Research models have demonstrated its selective binding properties and CNS-mediated effects. The peptide shows stability under proper storage conditions and maintains biological activity when handled according to established protocols.