Tesa Ipamorelin

Description

Product Overview

Featuring a precision-formulated blend of Tesamorelin (6mg) and Ipamorelin (2mg) peptides in a single research unit. Tesamorelin, a synthetic analog of growth hormone-releasing hormone (GHRH), demonstrates selective agonist activity at growth hormone-releasing hormone receptors, while Ipamorelin acts as a selective ghrelin receptor agonist (growth hormone secretagogue). Laboratory studies suggest this synergistic combination may potentially enhance growth hormone pathway signaling and related metabolic processes in controlled research models. Research indicates this blend could possibly influence pituitary growth hormone release mechanisms, IGF-1 pathway activation, and metabolic regulation cascades in tissue samples.
This research-grade product contains Tesamorelin (6mg) and Ipamorelin (2mg) combined in a single sterile vial for a total of 8mg peptide blend.

Quality Standards
Greater than 98% pure (combined peptides)
Endotoxin-free
Sterility guaranteed

Structure & Specification
Tesamorelin, Ipamorelin Blend Summary
Product Specifications: Lyophilized Powder (>98% purity) in 3ml vial.
*Requires Reconstitution with solvent such as BAC Water
Application: Research peptide blend with potential in growth hormone pathway and metabolic studies
Appearance: Solid, white to off-white powder in 3mL glass ampule
Tesamorelin Specifications:

Chemical Formula: C221H366N72O67S
CAS Number: 218949-48-5
Molecular Weight: 5135.8 g/mol
Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2

Ipamorelin Specifications:

Chemical Formula: C38H49N9O5
CAS Number: 170851-70-4
Molecular Weight: 711.9 g/mol
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2

Storage: Store at ≤-20°C, sealed, away from heat, light, and moisture.
Synonyms: TESA-IPA blend, Tesamorelin/Ipamorelin combination, GHRH/GHRS blend
Sourcing Standards

Raw ingredients manufactured by an FDA registered & audited supplier following cGMP standards
Finished peptides 0.22 µm sterile-filtered (aseptically processed) and produced in a GMP facility
Tested by a US FDA registered & audited third-party analytical lab accredited by ISO/IEC and U.S. Department of Ecology

Always Quality-Tested, Verified With Third Party COA’s
At every step, we prioritize quality by conducting rigorous third-party testing on all our products. These tests focus on four key characteristics: identity, purity, sterility, and endotoxicity, ensuring that each batch meets the highest standards for safety and performance, with independent third party Certificates of Analysis (COAs) to verify our commitment to excellence.
Identity Test
Identity testing ensures that both Tesamorelin and Ipamorelin are present in correct proportions as labeled, verifying authenticity and matching to established reference standards through advanced analytical methods including HPLC and mass spectrometry for each peptide component.
Purity Test
Purity and concentration testing verifies that both peptides are present in the correct amounts (6mg Tesamorelin, 2mg Ipamorelin), with combined purity of 98% or higher to meet stringent quality standards. Our analytical testing includes individual peptide quantification and blend ratio verification.
Sterility Test
Sterility testing ensures that the blended product is completely free from bacteria, fungi, and other microorganisms, meeting USP <71> sterility requirements for research-grade peptide combinations.
Endotoxin Test
Endotoxin testing confirms bacterial endotoxin levels are below detectable limits (<1.0 EU/mg), ensuring product safety and research integrity through LAL (Limulus Amebocyte Lysate) testing methods for the complete blend.

Research Applications

Growth hormone pathway synergy studies
GHRH and ghrelin receptor interaction research
Metabolic regulation mechanism investigation
Pituitary hormone release studies
IGF-1 pathway activation research
Growth hormone secretagogue comparative studies
Endocrine system signaling research
Body composition regulation studies

Handling & Storage Guidelines

Store lyophilized powder at -20°C or below
Protect from light and moisture
Once reconstituted, store at 2-8°C for short-term use (up to 7 days)
For long-term storage of reconstituted solution, store at -20°C
Avoid repeated freeze-thaw cycles
Use appropriate sterile technique during reconstitution
Consider peptide stability when planning experimental timelines

Research Notes
This Tesamorelin-Ipamorelin blend has been formulated based on research indicating potential synergistic effects between GHRH analogs and growth hormone secretagogues. Laboratory studies suggest that combining these peptides may enhance overall growth hormone pathway activation compared to individual peptide use. The 6mg:2mg ratio has been optimized based on published research examining effective dosing relationships between these compounds in experimental models.

Mechanism of Action
Tesamorelin: Functions as a selective GHRH receptor agonist, stimulating growth hormone release from anterior pituitary somatotroph cells through cAMP-dependent pathways.
Ipamorelin: Acts as a selective ghrelin receptor (GHSR-1a) agonist, promoting growth hormone secretion through distinct but complementary signaling mechanisms.
Synergistic Effects: The combination may provide enhanced and prolonged growth hormone response through dual pathway activation, potentially offering advantages in research applications studying growth hormone dynamics and metabolic regulation.